Medical engineering plays a more and more important role in driving the fundamental biology research moving forward. The work presented in this book targets at engineer smart parylene filters for various biomedical applications. Three smart parylene membranes are discussed, including parylene magnesium-embedded filter for circulating tumor cells isolation, parylene based microelectrode filter for single-islet electroisletogram, and parylene-on-PDMS membrane for vaccine production. Besides the three devices, parylene properties are also studied and a novel origami design is proposed, which can potentially increase the surface areas of the membranes by fold the 2D flat film into 3D structures. Details are discussed in the chapters.

Yang Liu, Ph.D., California Institute of Technology. Dr. Liu's research covers biomedical devices, Lab-on-a-chip, Bio-MEMS, and flexible implants. He has successfully developed devices like novel membrane filters, implantable sensors, and retinal prosthesis. Currently he is with Oracle Inc., Redwood City.